相关实验视频

Updated: Jun 23, 2025

In Vitro Polymerization of F-actin on Early Endosomes
12:15

In Vitro Polymerization of F-actin on Early Endosomes

Published on: August 28, 2017

9.0K

人类ESCRT-I和ALIX作为脚手架的螺旋状纤维 in vivo 的功能

Stephanie J Spada, Kevin M Rose, Paola Sette

    bioRxiv : the preprint server for biology
    |June 21, 2024
    PubMed
    概括

    运输所需的内体组分复合体 (ESCRT-I) 和ALIX蛋白质在细胞中形成螺旋状纤维. 这些纤维作为支架,结合核酸和模板ESCRT-III组件用于膜修复和病毒芽.

    更多相关视频

    Protein Extract Preparation and Co-immunoprecipitation from Caenorhabditis elegans07:22

    Protein Extract Preparation and Co-immunoprecipitation from Caenorhabditis elegans

    Published on: May 23, 2020

    8.9K
    Finite Element Modelling of a Cellular Electric Microenvironment08:23

    Finite Element Modelling of a Cellular Electric Microenvironment

    Published on: May 18, 2021

    3.4K

    相关概念视频

    Structural Protein Function01:56

    Structural Protein Function

    Structural proteins are a category of proteins responsible for functions ranging from cell shape and movement to providing support to major structures such as bones, cartilage, hair, and muscles. This group includes proteins such as collagen, actin, myosin, and keratin.
    Collagen, the most abundant protein in mammals, is found throughout the body. In connective tissue, such as skin, ligaments, and tendons, it provides tensile strength and elasticity.  In bones and teeth, it mineralizes to...
    27.6K
    Mechanism of Filopodia Formation01:39

    Mechanism of Filopodia Formation

    Filopodia are thin, actin-rich cellular protrusions that play an important role in many fundamental cellular functions. They vary in their occurrence, length, and positioning in different cell types, suggesting their diverse roles.
    Their main function is to guide migrating cells during normal tissue morphogenesis or cancer metastasis by recognizing and making initial contacts with the extracellular matrix. However, they can also act as stationary cell anchors or help to establish communication...
    2.3K
    Cytoskeletal Accessory Proteins01:13

    Cytoskeletal Accessory Proteins

    The cytoskeleton is an essential cell component that plays several structural and functional roles. However, the filaments that make up the cytoskeleton cannot function independently and depend on the accessory or ancillary proteins to effectively carry out their function. Accessory proteins associate with cytoskeletal filaments and their monomers, aiding filament formation and function. They also help in the cross-communication among cytoskeletal filaments. Cytoskeletal accessory proteins are...
    3.0K
    Assembly of Cytoskeletal Filaments01:18

    Assembly of Cytoskeletal Filaments

    Cytoskeletal filaments are polymeric forms of smaller protein subunits. However, individual cytoskeletal filaments may easily disassemble or associate with other similar filaments to form rigid structures. Microfilaments, made of actin monomers, rely on actin-binding proteins to form bundles and create networks of individual actin filaments. Microtubules rely on microtubule-associated proteins (MAPs) to form sturdy cylindrical structures. However, the proteins involved in forming complex...
    19.3K
    Formation of Intermediate Filaments00:57

    Formation of Intermediate Filaments

    Intermediate filaments are cytoskeletal proteins with higher tensile strength and flexibility than microfilaments and microtubules. Unlike the other two cytoskeletal proteins, intermediate filament formation lacks the enzymatic activity to hydrolyze nucleotides like ATP and GTP to generate energy for polymerization. Therefore, the formation of intermediate filaments is multistep self-assembly. The involvement of any accessory proteins in intermediate filament formation has not yet been...
    3.0K
    Actin Polymerization and Cell Motility01:13

    Actin Polymerization and Cell Motility

    Actin is a family of globular proteins that are highly abundant in eukaryotic cells. It makes up approximately 1-5% of total cell protein concentration. Actin monomers polymerize to form a complex network of polarized filaments, the actin cytoskeleton, that plays a crucial role in many cellular processes, including cell motility, division, endocytosis, and metastasis of cancer cells.
    Actin cytoskeleton dynamics can produce pushing, pulling, and resistance forces that help the cell to migrate....
    5.2K