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登革热的肺部表现:一项回顾性研究
Lakshmi B Keshav1, Adithi K2, Karan Malhotra3
1Medicine, Nottingham University Hospitals NHS Trust, Nottingham, GBR.
Cureus
|June 21, 2024
概括
肺部表现发生在超过10%的登革热患者中,增加了死亡风险,特别是在患有并发病的老年人中. 早期识别登革热的呼吸道症状对于改善患者的治疗结果至关重要.
科学领域:
- 医学研究 医学研究
- 传染病 传染病 传染病
- 肺部病理学 肺部病理学
背景情况:
- 登革热是一种蚊子传播的病毒性疾病,是全球日益严重的健康威胁,特别是在低收入和中等收入国家.
- 非典型的登革热表现,包括呼吸系统的参与,复杂的诊断和管理.
- 登革热的肺部并发症尚不清楚,但与毛细血管泄漏和血小板狭窄有关,可能会增加严重程度和死亡率.
研究的目的:
- 为了确定登革热患者肺部表现的发病率.
- 探索肺部参与和患者结果之间的相关性.
- 为了确定与登革热肺部表现相关的风险因素.
主要方法:
- 一项回顾性研究分析了2019年1月至12月在印度曼加罗尔的一家三级护理医院的255名登革热患者 (≥18岁).
- 数据包括人口统计,临床症状,实验室结果和成像 (胸部X射线,CT,超声波,心声波).
- 肺部表现的诊断依赖于临床评估和成像;统计分析使用SPSS (p<0.05显著性).
主要成果:
- 10.19% (26/255) 的登革热患者出现了肺部表现,最常见的是肺部溢液.
- 年龄较大 (>50岁) 和并发症与肺部感染的发病率较高有关.
- 患有肺部症状的患者表现出不同的实验室概况 (尿素,胆红素,肝酶升高;血小板减少) 和较高的死亡率.
结论:
- 肺部表现是登革热的重要并发症,与增加的发病率和死亡率有关.
- 早期检测呼吸道症状,特别是老年患者或患有并发症的患者,至关重要.
- 需要进一步的研究来了解登革热的肺病理生理学,并优化治疗以改善患者的预后.
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