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微塑料对怀孕和胎儿发育的影响:系统性审查

Raj Kishor Sharma¹, Usha Kumari², Sudhir Kumar³

¹Microbiology, Patna Medical College, Patna, IND.

|June 21, 2024

概括

微塑料 (MP) 污染对胎儿发育构成风险. 这次审查发现,胎盘和胎儿中的MP与出生体重降低和胎儿生长受损有关,这突显了需要更多研究的需要.

科学领域:

环境健康环境健康
毒理学毒理学毒理学
生殖科学生殖科学

背景情况:

微塑料 (MP) 污染是一个普遍存在的环境问题,可能会对人类健康产生影响.
产前暴露于微塑料及其对胎儿发育的影响仍未得到充分研究.
了解微塑料对怀孕的影响对于公众健康至关重要.

研究的目的:

系统地审查现有的关于微塑料对怀孕和胎儿发育的影响的文献.
在产前暴露的背景下综合有关微塑料存在,特征和影响的发现.
识别知识缺口,指导未来在这个关键领域的研究.

主要方法:

从2010年到2024年3月,在主要的科学数据库 (PubMed,Embase,Web of Science,Scopus,ScienceDirect,Google Scholar) 中进行了全面的文献搜索.
专注于微塑料,怀孕和胎儿发育的原始研究文章被选择和审查.
数据提取和质量评估由两名独立审查员使用Joanna Briggs Institute (JBI) 批判性评估清单进行.

主要成果:

包括12项涉及234名受试者的研究,发表于2021年至2024年,主要来自中国.
在胎盘组织和胎儿体内检测到微塑料 (2.1100μm).
在生活方式因素,胎盘中MP存在,降低出生体重,改变妊娠年龄和胎儿发育受损之间观察到相关性.

结论:

怀孕期间接触微塑料可能会对胎儿发育产生不利影响.
在胎盘和胎儿中确认了微塑料的存在.
进一步进行广泛的研究是必不可少的,以充分阐明怀孕期间与微塑料暴露相关的风险.

关键词:

内分泌干扰物干扰内分泌干扰物胎儿的发育胎儿的发育微塑料微塑料的使用怀孕怀孕怀孕怀孕怀孕生殖健康生殖健康

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Teratogenicity

Teratogenicity

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