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队列概况:约翰霍普金斯COVID长期研究 (JHCLS) - 一项美国全国性的前性队列研究
Eryka Wentz1, Zhanmo Ni2, Karine Yenokyan3
1Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA ewentz1@jhu.edu.
BMJ open
|June 21, 2024
概括
约翰霍普金斯COVID长期研究跟踪了超过17,000名成年人的长期COVID症状. 大多数参与者在急性感染期间出现症状,63%的人符合长期COVID定义.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- COVID-19 (冠状病毒疾病2019) 在全球范围内带来了重大的短期和长期健康挑战.
- SARS-CoV-2 感染的急性后续症状,通常称为长期COVID,表现为影响多个器官系统的广泛症状.
- 了解长期COVID症状的自然史,进展和解决对于患者护理和公共卫生策略至关重要.
研究的目的:
- 为了前性地调查COVID-19的短期和长期后果.
- 为了检查随着时间的推移与长期COVID相关的症状的进展和解决.
- 分析有或没有SARS-CoV-2感染史的个体的数据.
主要方法:
- 约翰霍普金斯COVID长期研究利用在线调查收集自我报告数据.
- 这项研究包括一大群成年人,其中许多人有SARS-CoV-2感染史.
- 描述了参与者的基线特征,包括感染前的健康状况和急性COVID-19症状.
主要成果:
- 这项研究招募了16764名有SARS-CoV-2感染史的成年人和799名对照人.
- 在那些有感染史的人中,75%的人报告感染前健康状况良好,99%的人经历了急性症状,9.9%的人被住院治疗.
- 使用世卫组织的定义,有63%的参与者有感染史被归类为长期COVID.
结论:
- 这个队列概况为正在进行的约翰霍普金斯COVID长期研究提供了基线数据.
- 这项研究有利于检查长期COVID症状的纵向过程.
- 未来的分析将集中在一个大,多样化的队列中的症状进展和解决的动态.
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