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Updated: Jun 23, 2025

Detecting the Ligand-binding Domain Dimerization Activity of Estrogen Receptor Alpha Using the Mammalian Two-Hybrid Assay
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Published on: December 19, 2018

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使用新型芳香桥梁单位点击雌激醇二元:合成和抗癌评估

Jiří Řehulka1, Michal Jurášek2, Pavel Dráber3

  • 1Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University, Olomouc, Czech Republic.

Journal of enzyme inhibition and medicinal chemistry
|June 21, 2024
PubMed
概括

新的雌激醇二元体 (EDs) 通过破坏蛋白动力学,显示出强大的抗癌作用. 化合物ED3和ED5表现出优越的细胞毒性和抗血管性质,提供有前途的治疗潜力.

关键词:
雌二醇是雌二醇的一种.癌细胞是一种癌细胞.这就是Dimer Dimer的意思.在的中.管道中的管道.

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Removing one hydrogen from the intervening CH2 group...
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