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Updated: Jun 23, 2025

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
00:06

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Published on: August 20, 2019

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肠道病毒3A蛋白质通过与GBF1的相互作用来破坏内质网膜恒常性

Junki Hirano1,2,3, Tsuyoshi Hayashi3, Kouichi Kitamura3

  • 1Laboratory of Virus Control, Center for Infectious Disease Education and Research (CiDER), Osaka, Japan.

Journal of virology
|June 21, 2024
PubMed
概括

肠道病毒通过劫持高尔基特异性brefeldin A-耐药瓜核酸交换因子1 (GBF1) 破坏细胞蛋白折叠,导致未折叠的蛋白质反应 (UPR) 和细胞死亡. 准PERK/CHOP通路可以治疗肠道病毒感染.

关键词:
压力ERER压力ERER压力GBF1GBF1GBF1GBF1GBF1GBF1GBF1GBF1GBF1GBF1佩克 (Perk) 是一个名牌.灭症 (apoptosis) 是一种死亡的过程.肠道病毒病毒.不折叠的蛋白质反应反应

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