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Updated: Jun 23, 2025

Differentiated Mouse Adipocytes in Primary Culture: A Model of Insulin Resistance
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甲状腺刺激激素通过内质网膜应激诱导脂肪细胞中的胰岛素抵抗

Qing Zhou1, Li Yong Zhang2, Mei Feng Dai3

  • 1Department of Endocrinology, Fujian Maternity and Child Health Hospital, Fujian Children's Hospital, Fuzhou, China.

Endocrine connections
|June 21, 2024
PubMed
概括

甲状腺刺激激素 (TSH) 通过激活内网膜 (ER) 应激和JNK通路,直接导致脂肪细胞的胰岛素抵抗. 这个过程会损害葡萄糖的吸收,并且可以通过阻断ER压力来逆转.

关键词:
脂肪细胞 (adipocytes) 是一种脂肪细胞.细胞内膜网膜的压力应激胰岛素耐药性是一种胰岛素耐药性.甲状腺刺激激素激素激发甲状腺刺激激素.

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