血型是心血管内关节切除术后的长期心血管风险因素
Filipa Jácome1,2, Mariana Basílio Martins1, Alexandre Sarmento2
1Department of Angiology and Vascular Surgery, Centro Hospitalar Universitário de São João, Porto, Portugal.
Acta chirurgica Belgica
|June 21, 2024
概括
血液型影响心血管风险,在心动脉内关节切除术后. 非O型血型显示较高的长期风险的主要不良心血管事件,而Rh阴性患者面临的术后风险增加.
科学领域:
- 血管外科 血管外科
- 心脏病学 心脏病学
- 血型遗传学 血型遗传学
背景情况:
- ABO血型与心血管疾病风险有关.
- rhesus (Rh) 因子也显示了与心血管结果的初步关联.
- 动脉内关节切除术 (CEA) 是一种治疗动脉狭窄的手术.
研究的目的:
- 调查 ABO 和 Rh 血型对 CEA 后短期和长期结果的影响.
- 分析血型与主要心血管不良事件 (MACE),死亡率和术后并发症之间的关联.
- 为了确定基于血型的潜在风险分层策略.
主要方法:
- 针对动脉样硬化性大脑管狭窄症 (2012-2019) 进行CEA的184名患者的前性随访.
- 主要结局:长期MACE和全因死亡率. 二次结局:非心脏手术 (MINS) 后的术后并发症和心肌损伤.
- 时间到事件分析用于评估ABO和Rh组的影响.
主要成果:
- 非O型血型与冠状动脉疾病的发病率较高有关 (OR:2.313,p=0.008).
- резус阳性患者患有更多的充血性心力衰竭 (14.7%,p=0.03).
- 长期MACE发生率在非O患者中较高 (aHR:2.034,p=0.040),而术后MINS在Rh阴性患者中更为常见.
结论:
- 非O型血型与CEA后长期MACE增加有关.
- 阴性血型与30天MINS的更高发病率有关.
- 术前的心脏评估可能需要对特定血型进行更全面的评估.
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