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双重植入Xen 45凝支架在初级开角光眼中:一个试点研究
Andrea Grosso1,2, Piero Ceruti3, Jacopo Garlasco4
1Ophthalmology Unit, ASL Alessandria "Santo Spirito" Hospital, Casale Monferrato, Italy. 78andreagrosso@gmail.com.
International ophthalmology
|June 21, 2024
概括
双重植入Xen 45凝支架 (Xen),采用微侵袭的外部方法,有效降低了青光眼患者的眼内压力 (IOP). 这种连续的Xen支架程序表明了有利的安全性和有效性概况.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼的手术 玻璃眼的手术
- 医疗器械 医疗器械
背景情况:
- 主要开角青光眼 (POAG) 管理通常需要干预降低眼内压力 (IOP).
- 克森45凝支架是一种用于降低IOP的微创装置.
- 顺序植入眼装置是一种不断发展的外科战略.
研究的目的:
- 为了评估Xen 45凝支架 (Xen) 双重植入的结果,使用关闭结膜的外部方法.
- 评估第二次Xen支架植入同一眼中的安全性和有效性.
主要方法:
- 追溯的单中心案例系列.
- 包括8名POAG.患者的8个伪眼睛.
- 在第二次Xen植入物后至少六个月的随访通过ab externo技术,没有结膜开口.
主要成果:
- 平均内血压从手术前的30mmHg下降到第一个Xen植入物后的22.4mmHg (p=0.0092).
- 在第二次Xen植入后,六个月后,内压进一步下降至16.1mmHg (p=0.0183).
- 没有观察到有意义的手术内或术后并发症;3名患者需要额外的医疗治疗.
结论:
- 通过关闭结膜的外部方法连续植入两个Xen 45凝支架是一种有前途的程序.
- 该技术在这个小案例系列中显示出了有利的安全性和有效性概况.
- 需要进行进一步的研究来评估这种对格洛科马治疗的方法.
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