定义一种特定的维生素A5/X缺乏症 - - 维生素A5/X作为心理健康的关键饮食因素
Diána Bánáti1, Julian Hellman-Regen2, Isabelle Mack3
1Department of Food Engineering, Faculty of Engineering, University of Szeged, Hungary.
概括
食维生素A5 / X对于神经系统的健康至关重要,激活视网膜X受体 (RXR) 信号. 这一途径影响髓化,多巴胺和神经保护,支持大脑衰老和预防疾病.
科学领域:
- 神经科学是一个神经科学.
- 营养科学 营养科学
- 分子生物学分子生物学
背景情况:
- 均衡的饮食对于神经系统的功能至关重要.
- 视网膜X受体 (RXR) 介导的信号传递是饮食依赖生理过程的关键途径.
- 在蔬菜中发现的维生素A5 / X是一种用于RXR信号的新型维生素前体.
研究的目的:
- 审查维生素A5/X的科学基础及其在RXR介导信号传递中的作用.
- 探索对神经系统健康,大脑衰老和疾病预防的影响.
- 提供营养和药理方面的建议.
主要方法:
- 现有科学研究的文献综述.
- 通过维生素A5/X激活RXR的分子机制的分析.
- 关于生理和神经保护功能数据的综合.
主要成果:
- 维生素A5/X,通过其活性形式9-cis-13,14-dehydroretinoic acid (9CDHRA),可以激活RXR.
- 激活RXR启动了涉及PPAR,LXR,VDR和RAR的信号级联.
- 通过RXR介导的信号影响多巴胺,髓化,粉样β清除和神经炎症.
结论:
- 维生素A5 / X作为关键激素信号通路的营养开关,维持平衡.
- 维生素A5 / X-RXR信号传递对心理健康,健康的大脑衰老以及预防神经疾病和成至关重要.
- 这条通路对于髓化和大脑清理过程也至关重要.
更多相关视频
05:03Author Spotlight: Investigating Physiological Functions of Vitamin A Transporters Using HPLC-Based Vitamin A Profiling
Published on: December 27, 2024
1.1K
10:46A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
Published on: December 9, 2015
10.7K
相关概念视频
Vitamins
670
Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
670
Role of Skin in Vitamin D Synthesis
5.1K
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
5.1K
Photoreceptors and Visual Pathways
6.0K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
6.0K
Role of Vitamins in Maintaining Bone Health
3.2K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
3.2K
Depression: Overview
238
Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
238
Role of Neurotransmitters in Memory
521
Neurotransmitters are integral to the brain's communication system, enabling neurons to transmit signals across synapses. This chemical exchange underpins various cognitive functions, including memory processes. The role of neurotransmitters in memory is multifaceted, influencing the encoding, consolidation, and retrieval of memories through their action on different neural circuits.
Glutamate and Synaptic Plasticity
Glutamate, the brain's main excitatory neurotransmitter, is...
Glutamate and Synaptic Plasticity
Glutamate, the brain's main excitatory neurotransmitter, is...
521
