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Updated: Jun 23, 2025

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Taste Exam: A Brief and Validated Test
Published on: August 17, 2018
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TAS2R38 苦味受体遗传变异与韩国人的饮食质量有关
Hae Young Kim1, Jeong-Hwa Choi1
1Department of Food Science and Nutrition, Keimyung University, Daegu, 42601, South Korea.
Appetite
|June 21, 2024
概括
苦味受体TAS2R38基因的遗传变异会影响韩国人的饮食质量. 这些关联在肥胖个体中更为明显,影响肉类消费和饮食适度.
科学领域:
- 营养基因组学 营养基因组学
- 人类遗传学 人类遗传学
- 饮食科学 饮食科学
背景情况:
- 味觉受体2型,成员38 (TAS2R38) 基因的遗传变异会影响苦味的感知.
- 苦味敏感性与食物偏好,消费模式和整体饮食质量有关.
研究的目的:
- 调查TAS2R38遗传变异与韩国人口的整体饮食质量之间的关联.
- 使用韩国健康饮食指数 (KHEI) 对TAS2R38双型和肥胖状况进行饮食质量分析.
主要方法:
- 来自韩国基因组和流行病学研究的41,839名韩国成年人的TAS2R38双型 (rs713598,rs1726866,rs10246939) 的分析.
- 评估一般特征,KHEI分数和肥胖状况.
- 统计分析以确定TAS2R38基因型,肥胖和KHEI组件之间的关联.
主要成果:
- 在非肥胖个体中,AVI/AVI双型与与PAV/*双型相比更高的"白肉与红肉的比例"有关.
- 在肥胖个体中,PAV/*双型与AVI/AVI双型相比,对"适度"和总KHEI的得分更高.
- 观察到TAS2R38基因变异与肥胖之间的相互作用是"白肉与红肉的比例"",适度"和KHEI总分.
结论:
- TAS2R38遗传变异与韩国人口的整体饮食质量有关.
- TAS2R38基因型对饮食质量的影响在肥胖患者中更为显著.
- 研究结果强调了遗传学,肥胖和饮食模式之间的相互作用.
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