对心血管疾病检测的负责任人工智能:朝着保护隐私和可解释的模型发展
Mahbuba Ferdowsi1, Md Mahmudul Hasan2, Wafa Habib3
1Department of Mechatronics and Biomedical Engineering, Lee Kong Chian Faculty of Engineering and Science, Universiti Tunku Abdul Rahman (UTAR), Kajang, Selangor 43200, Malaysia.
这项研究开发了一种负责任的AI模型,用于使用差异隐私和可解释方法预测心血管疾病 (CD). 该方法确保了准确的CD风险评估,同时保护患者数据隐私并促进对医疗保健AI的信任.
科学领域:
- 医疗信息学 医疗信息学
- 医疗保健中的人工智能
- 数据 隐私 数据 隐私 数据
背景情况:
- 心血管疾病 (CD) 是全球主要的死亡原因,需要改进早期检测方法.
- 人工智能 (AI) 为医疗保健中的风险评估和结果预测提供了潜力,但也引发了对数据隐私和偏见的担忧.
- 负责的人工智能开发对于敏感的医疗保健应用至关重要,强调隐私,安全,透明度和公平性.
研究的目的:
- 开发和实施一个负责任的AI模型用于心血管疾病 (CD) 预测.
- 在AI模型中优先考虑患者隐私和数据安全.
- 确保医疗保健人工智能应用程序的透明度,可解释性,公平性和道德遵守.
主要方法:
- 采用数据匿名化技术,包括对敏感特征添加拉普拉斯噪声.
- 利用差异性隐私 (DP) 框架进行强大的数据隐私保护.
- 综合特征选择,统计分析和可解释性工具 (SHAP,LIME) 为模型透明度,比较性能与物流回归 (LR),高斯素朴贝叶斯 (GNB) 和随机森林 (RF).
主要成果:
- 使用LR的DP框架表现出有希望的性能,AUC为0.848±0.03,准确度为0.797±0.02.
- 性能指标,包括精度,回忆和F1分数,与非隐私框架相比,表明有效性.
- SHAP和LIME分析支持了临床发现,强调了模型的透明度和与负责任的AI原则的一致性.
结论:
- 支持一种新的CD预测方法,将数据匿名化,DP和可解释性工具 (SHAP,LIME) 结合起来.
- 负责任的AI框架确保了准确的预测,保护了患者的隐私,并促进了用户对医疗保健AI的信任.
- 这项研究为预测CD提供了至关重要的工具,有可能预防死亡事故并改善全球患者的治疗结果.
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