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Updated: Jun 23, 2025

DNAzyme-dependent Analysis of rRNA 2’-O-Methylation
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DNAzyme-dependent Analysis of rRNA 2’-O-Methylation

Published on: September 16, 2019

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在mRNA内部的2'-O-甲基化促进了mRNA的稳定性

Yanqiang Li1, Yang Yi2, Xinlei Gao1

  • 1Basic and Translational Research Division, Department of Cardiology, Boston Children's Hospital, Boston, MA, USA; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.

Molecular cell
|June 21, 2024
PubMed
概括

这项研究表明,信使RNA (mRNA) 上的2'-O-甲基化 (Nm) 增强了它们的稳定性和表达. 纤维拉林介导的Nm修饰与癌症途径和3' UTR缩短,调节基因表达有关.

关键词:
通过2′-O-甲基化.在CPSF7中.在FBL和FBL.RNA 稳定性 RNA 稳定性替代性的多基化.标志性转录组学 标志性转录组学在mRNA修改过程中.机器学习是机器学习.这是一个纳米孔.前列腺癌是前列腺癌.

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