疲劳测试方法来评估静脉支架50年的耐用性
Jeffrey H Vogel1, Christopher P Cheng2, Erin H Murphy3
1Peripheral Vascular Health, Medtronic, Minneapolis, MN, USA.
概括
这项研究引入了一种新的体外试验方法,用于测试 iliofemoral静脉阻塞性疾病的支架耐用性. 专用静脉支架在模拟长期使用下,与非静脉支架相比,表现出更好的疲劳抵抗力.
科学领域:
- 血管外科 血管外科
- 生物医学工程 生物医学工程
- 材料科学 材料科学 材料科学
背景情况:
- 阴腰腹静脉阻塞性疾病显著影响生活质量.
- 年轻的患者需要长期的支架通透性 (几十年) 静脉疾病.
- 穿过 inguinal 带放置的支架面临动态应力,可能发生骨折.
研究的目的:
- 描述一个实验室50年支架疲劳测试方法.
- 评估支架耐用性,以防动态应力诱导的骨折.
- 评估新型静脉支架的长期性能.
主要方法:
- 模拟部曲穿过 inguinal 带,模仿坐到站运动.
- 利用文献审查,尸体研究和计算机建模来定义载荷.
- 在模拟50年疲劳条件下对尼醇支架的试验.
主要成果:
- 部曲导致非静脉尼丁醇支架的骨折.
- 专用静脉支架显示出更好的耐用性,50年后只有15%的骨折.
- 非静脉支架在1.4年内出现更高的骨折率 (35%).
结论:
- 开发的疲劳测试方法适用于评估静脉支架的耐用性.
- 与非静脉支架相比,静脉支架表现出优越的耐疲劳性.
- 该方法有助于评估用于静脉疾病的设备的长期性能.
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