状态与老年中国成年人甲状腺激素和甲状腺功能障碍有关
Feng Li1, Liqin Su2, Ranqi Shao1
1China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, 100050, China.
Biological trace element research
|June 21, 2024
概括
这项研究发现,老年中国人的较高水平与较低的甲状腺刺激激素和降低甲状腺功能低下的风险有关. 然而,的升高也与甲状腺功能障碍的风险增加有关.
科学领域:
- 内分泌学 在内分泌学.
- 营养科学 营养科学
- 老年病的医生 老年病的医生
背景情况:
- (Se) 对于甲状腺激素代谢至关重要.
- 关于老年人群中的状况和甲状腺功能的流行病学数据很少,并且存在矛盾.
研究的目的:
- 调查老年中国人的状况和甲状腺功能之间的关联.
- 探索水平与甲状腺功能低下症和甲状腺功能过高症风险之间的关系.
主要方法:
- 涉及老年参与者 (≥65岁) 的横截面研究.
- 收集指甲和全血样本用于度分析.
- 使用血清甲状腺激素评估甲状腺功能:TSH,TT3,TT4,FT3和FT4.
主要成果:
- 在全血和指甲度之间发现了显著的正相关性 (r = 0.672,P < 0.001).
- 较高的水平 (在血液和指甲中) 与较低的TSH和较高的TT3,FT3和FT4水平有关.
- 的升高与降低甲状腺功能障碍的风险和增加甲状腺功能障碍的风险有关.
结论:
- 的状态与中国老年人口的甲状腺激素水平有显著的关联.
- 更高的摄入量可能会预防甲状腺功能低下症,但可能会增加甲状腺功能障碍症的风险.
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