韩国老年多药患者常用和潜在不合适药物的趋势
Woo-Young Shin1, Tae-Hwa Go2, Jung-Ha Kim3
1Department of Family Medicine, Chung-Ang University College of Medicine, 102 Heukseok-ro, Dongjak-gu, Seoul, 06973, Republic of Korea.
BMC geriatrics
|June 21, 2024
概括
多药在韩国老年人中越来越多. 潜在的不适当的药物使用仍然存在,特别是在老年人群中,需要更好的管理策略.
科学领域:
- 老年学是一门学科.
- 公共卫生 公共卫生
- 药理学 药理学是指药理学的学科.
背景情况:
- 多药是一种重要的全球公共卫生问题.
- 老年人特别容易受到与多药学相关的风险的影响.
- 了解这群人群中药物使用模式对于患者安全至关重要.
研究的目的:
- 为了确定多药在韩国老年患者中的患病率.
- 分析常见处方药的使用趋势.
- 在这个人群中调查潜在不合适药物的使用 (PIMs).
主要方法:
- 利用了来自韩国国家健康信息数据库 (2014-2018) 的数据.
- 包括65岁及以上的个人处方任何药物.
- 雇佣的Joinpoint回归用于趋势分析和奇平方测试用于处方费率比较.
主要成果:
- 多药性影响了1.85万老年人中的35.7%,从2014年至2018年年龄调整后的比例增加.
- 通常处方的药物包括阿司匹林,阿托瓦斯塔丁和甲胺.
- 潜在不合适的药物,如阿尔普拉佐拉姆 (alprazolam) 和迪亚泽巴姆 (diazepam) 显示,整体使用量下降,但在≥85岁的年龄组增加.
结论:
- 韩国老年人中多药药的流行率正在上升.
- 使用PIMs,包括二和三环抗抑郁药,仍然是一个问题,特别是在最老的患者.
- 这些发现支持有针对性的多药房管理战略的需要,以提高药物安全.
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