使用基于智能手机的自我管理平台研究帕金森病的性别差异:多中心,横截面试点研究
Zhiheng Xu1, Lirong Jin2, Weijie Chen3
1Department of Neurology and National Research Center for Aging and Medicine & National Center for Neurological Disorders, State Key Laboratory of Medical Neurobiology, Huashan Hospital, Fudan University, Shanghai, 200040, China.
BMC medical informatics and decision making
|June 21, 2024
概括
在帕金森病 (PD) 患者报告结果 (PROs) 中的性别差异是使用智能手机平台确定的. 女性报告了更多的抑郁症和动力障碍,而男性报告了更多的低血压和白天嗜睡.
科学领域:
- 神经学 神经学
- 数字健康数字健康
- 患者报告的结果
背景情况:
- 患者报告的结果 (PROs) 对于理解临床特征至关重要.
- 远程PRO测量是医疗保健领域的最新进展.
- 帕金森病 (PD) 中的性别差异PROs仍未得到充分研究.
研究的目的:
- 为了研究帕金森病患者中PROs的性别差异.
- 评估基于智能手机的平台对远程PRO数据收集的实用性.
主要方法:
- 基于智能手机的自我管理平台被用于远程PRO测量.
- 1828名帕金森病患者 (1001名男性,827名女性) 完成了PRO提交.
- 数据分析的重点是确定报告结果的统计学上显著的基于性别的变化.
主要成果:
- 在PRO中观察到显著的性别差异.
- 女性的身高,体重和BMI都比男性低.
- 女性报告了更高的抑郁和动力障碍率;男性报告了更多的低血和白天嗜睡.
结论:
- 该研究提供了PD患者报告结果中明显的性别差异的证据.
- 这些发现强调了在PD临床决策中考虑性别的重要性.
- 通过智能手机平台进行远程PRO测量对于PD患者来说是可行的和有效的.
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