相关实验视频

Updated: Aug 5, 2026

Depletion and Reconstitution of Macrophages in Mice
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Depletion and Reconstitution of Macrophages in Mice

Published on: August 1, 2012

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阻止M2-Like巨细胞两极化使用诱性寡氧核酸基因疗法 防止胰腺癌治疗的免疫逃避

Chang-Jung Chen1, Hao-Chen Wang1,2,3, Ya-Chin Hou1,4

  • 1Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

Molecular cancer therapeutics
|June 22, 2024
PubMed
概括

研究人员发现了活性氧物种 (ROS) 如何影响胰腺癌中M2类巨细胞两极分化. 一种新型的基因疗法使用诱性寡氧核酸 (ODN) 向STAT6和CYBB,显示出抑制M2样两极化和控制瘤生长的潜力.

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Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.