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四十年的尾神经刺激头痛疾病:一个系统的审查

Linda Kollenburg¹, Erkan Kurt^1,2, Wim Mulleners^2,3

¹Department of Neurosurgery, Radboud University Medical Center, Nijmegen, The Netherlands.

Current pain and headache reports

|June 22, 2024

概括

尾神经刺激 (ONS) 为慢性头痛疾病提供了一种安全有效的替代方案,这些疾病对传统治疗无反应. 这次审查强调了ONS的重点.

科学领域:

神经学神经学
神经外科神经外科

背景情况:

慢性头痛是全球主要的健康负担,许多患者经历了治疗耐药性或不良反应.
传统疗法往往不足以治疗难以治愈的头痛病例,需要采用替代方法.

研究的目的:

综合审查部神经刺激 (ONS) 对头痛疾病的疗效,安全性,机制和实际使用.
评估ONS作为慢性,难治的头痛患者的潜在替代方案.

主要方法:

对治疗头痛的尾神经刺激现有文献进行系统审查.
分析报告的应答率,长期有效性和与ONS相关的不良事件.

主要成果:

在集群头痛 (35.7-100%),慢性偏头痛 (17-100%) 和部神经疼痛 (63-100%) 中,ONS表现出显著的响应率.
长期有效性显示,41.6-88.0%的患者在18.3个月后仍然有反应.
常见的不良事件包括迁移/骨折 (13%),局部疼痛 (7.3%),表明一般有利的安全性.

结论:

尾神经刺激是慢性难治性头痛疾病的安全有效治疗选择.
建议与更大的队列进行进一步的研究,以支持ONS的更广泛的临床采用.

关键词:

慢性偏头痛是一种慢性偏头痛.集群头痛集群头痛是指集群头痛.半头脑是一个半头脑.头神经刺激的刺激尾神经疼痛是什么意思

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