呼吸练习对间歇性肺病患者的影响:系统性审查和元分析
Jia Fan1, Yuyang Chang2, Siming Cheng3
1Department of Respiratory and Critical Care Medicine, The Second Hospital of Jilin University, Changchun, 130022, Jilin, China.
概括
呼吸练习显著改善间歇性肺病 (ILD) 患者的肺功能,运动能力和生活质量. 这些练习是安全有效的,特别是当它们被整合到肺部康复计划中时.
科学领域:
- 肺部病理学 肺部病理学
- 呼吸系统医学 呼吸系统医学
- 康复 康复 康复 康复
背景情况:
- 间歇性肺部疾病 (ILD) 包含一组慢性肺部疾病,其特征是渐进性纤维化.
- 患有ILD的患者经常经历肺功能受损,运动能力降低和生活质量下降.
- 呼吸练习是一种非药物干预,用于控制ILD的症状和改善结果.
研究的目的:
- 对患有间歇性肺病 (ILD) 的患者进行呼吸练习的疗效和安全性进行综合分析.
- 为了比较各种对照组,ILD亚型,炼方法和持续时间对临床结果的影响.
- 评估呼吸练习在改善ILD患者关键健康指标方面的整体有效性.
主要方法:
- 在包括PubMed在内的9个电子数据库中进行了系统的文献搜索,截至2024年2月12日.
- 两位独立研究人员进行了研究选择,数据提取和质量评估 (Cochrane偏差风险工具).
- 数据分析使用RevMan 5.4和STATA 17.0软件,包括子组分析.
主要成果:
- 在ILD患者中,呼吸练习显著改善肺功能 (FVC%pred,DLCO%pred),减少呼吸困难 (MRC/mMRC尺度),增强运动能力 (6MWD),改善与健康有关的生活质量 (SGRQ).
- 亚组分析表明,随着通常的护理控制,不同ILD亚型 (混合,已知原因,纤维化) 的不同程度的益处和不同程度的益处得到了一致的改善.
- 呼吸练习单独改善了DLCO%pred,MRC/mMRC和SGRQ,当与肺部康复 (PR) 整合时,观察到更大的好处.
结论:
- 呼吸练习为改善ILD患者的肺功能,运动能力和HRQoL提供了安全有效的干预措施,无论干预的持续时间如何,都有显著的益处.
- 呼吸练习的有效性可能因ILD亚型而异,并且将其纳入肺部康复计划似乎特别有益.
- 对于进行呼吸练习的ILD患者来说,没有发现任何重大安全问题.
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