精神分裂症的日常功能:有氧耐力和骨肌肉强度的影响
Mathias Forsberg Brobakken1, Mona Nygård2, Einar Vedul-Kjelsås3
1Faculty of Health and Social Sciences, Molde University College, Molde, Norway; Department of Psychosis and Rehabilitation, Psychiatry Clinic, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.
空气性耐力,而不是肌肉力量,显著影响精神分裂症患者的日常功能. 氧气吸收峰值 (V·O2峰值) 和负面症状是功能表现的关键预测因素.
科学领域:
- 精神病学和心理健康 精神病学和心理健康
- 运动生理学 运动生理学
- 康复科学 康复科学 康复科学
背景情况:
- 精神分裂症患者经历了严重的身体健康问题,导致身体功能减弱和社会成本增加.
- 精神分裂症患者的有氧耐力和骨肌肉力量通常会减少,影响认知和整体功能.
- 在精神分裂症患者中,有氧能力和肌肉力量对功能技能和日常任务执行的具体贡献仍未得到充分研究.
研究的目的:
- 研究精神分裂症患者的有氧耐力 (氧气吸收峰值,V·O2峰值) 和骨肌肉力量 (1RM) 与功能技能和表现之间的关系.
- 确定VO2峰值,肌肉力量,年龄和负面症状对功能结果的独立和综合贡献.
主要方法:
- 一项涉及48名诊断为精神分裂症谱系障碍的门诊患者的横截面研究.
- 使用UCSD基于绩效的技能评估简报 (UPSA-B) 评估功能技能,并通过特定功能水平 (SLOF) 尺度评估功能表现.
- 测量氧气吸收峰值 (V̇O2peak),腿部压力最大肌肉力量 (1RM) 和机械功率,以及正负综合征量表 (PANSS).
主要成果:
- 氧气吸收峰值 (V·O2峰值) 与UPSA-B表现和SLOF身体功能,个人护理和活动有显著的关联.
- 最大肌肉力量 (1RM) 与SLOF身体功能有关,但与UPSA-B性能无关.
- 层次回归表明,VO2峰值,年龄和负面症状共同解释了功能性表现差异的很大一部分,1RM的贡献在年龄调整后减少.
结论:
- 在预测精神分裂症患者的功能技能和日常活动方面,有氧耐力 (V·O2峰值) 比最大肌肉力量 (1RM) 发挥更为关键的作用.
- V̇O2峰值,年龄和负面症状的组合显著影响功能表现,突出了因素的复杂相互作用.
- 针对有氧健身的干预措施对于改善精神分裂症患者的功能结果至关重要,除了管理负面症状和考虑与年龄相关的变化外.
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