常规查血清测试,以检测底层甲状腺和自身免疫性疾病在患有Moyamoya疾病的患者
Kei Ito1, Shoko Hara1, Motoki Inaji1
1Department of Neurosurgery, Tokyo Medical and Dental University, Tokyo, Japan.
Clinical neurology and neurosurgery
|June 22, 2024
概括
针对甲状腺疾病的常规查对莫亚莫亚病患者,特别是女性有益,以检测隐藏的甲状腺疾病. 在没有特定症状的情况下,不建议对其他自身免疫性疾病进行查.
科学领域:
- 神经学 神经学
- 内分泌学 在内分泌学.
- 免疫学 免疫学 免疫学
背景情况:
- 莫亚莫亚病 (MMD) 越来越多地与甲状腺和自身免疫性疾病有关.
- 对于MMD患者这些并发病的常规查血清测试的有用性仍然不确定.
研究的目的:
- 为了评估患有偶发性Moyamoya疾病的患者的甲状腺和自身免疫疾病的常规血清查的诊断产量.
- 为了确定这些查测试是否可以识别以前未被诊断的疾病.
主要方法:
- 对459名没有甲状腺或自身免疫性疾病史的MMD患者进行了回顾性分析.
- 2016年至2023年间对甲状腺激素,自身抗体和特定自身免疫标记物的查血清测试结果的评估.
主要成果:
- 42.6%的患者显示了异常的查结果.
- 5.9%是新确诊的甲状腺疾病 (Graves, Hashimoto,其他).
- 没有检测到非甲状腺自身免疫性疾病;新诊断的患者更多的是女性 (96.3%vs72.2%).
结论:
- 常规的甲状腺相关血清查对检测MMD患者,特别是女性的隐性甲状腺疾病具有临床价值.
- 没有相应的症状,不建议对非甲状腺自身免疫性疾病进行查.
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