相关实验视频

Updated: Jun 23, 2025

Following the Dynamics of Structural Variants in Experimentally Evolved Populations
04:52

Following the Dynamics of Structural Variants in Experimentally Evolved Populations

Published on: February 3, 2023

955

由代模板开关形成的反向三倍化会在基因组疾病位置产生结构变异多样性

Christopher M Grochowski1, Jesse D Bengtsson2, Haowei Du1

  • 1Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.

Cell genomics
|June 22, 2024
PubMed
概括

复杂的基因组重组,如重复-三倍化/反向重复 (DUP-TRP/INV-DUP),是疾病的关键. 这项研究解决了它们的结构,显示反向重复驱动这些致病性DNA突变.

关键词:
在MECP2重复综合征中.这是一个MMBIR,MMBIR.孟德尔的疾病是孟德尔的疾病.在Xq2828上使用.破裂诱导的复制.复制号码的变体是复制数的变体.逆转 逆转 逆转 逆转 逆转再组合的复合方式.分段复制的重复.模板切换的切换模式

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