分解处理速度:对第一发精神病和未受影响一级亲属的运动和认知见解
Ángel Yorca-Ruiz1, Rebeca Magdaleno Herrero1, Víctor Ortiz García de la Foz2
1Department of Molecular Biology, Faculty of Medicine, University of Cantabria, Santander, Spain; Department of Psychiatry, Valdecilla Biomedical Research Institute, Santander, Spain.
Spanish journal of psychiatry and mental health
|June 22, 2024
概括
第一次精神病发作 (FEP) 患者和亲属的处理速度缺陷显示出明显的运动和认知因素关系. 这些差异表明,认知障碍背后存在着各种各样的补偿策略.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 精神病学是一个精神病学.
背景情况:
- 处理速度 (PS) 缺陷是精神分裂症,第一发精神病 (FEP) 和他们的亲属认知障碍的核心特征.
- 由于运动和认知子组件的不同参与,评估PS是复杂的.
研究的目的:
- 调查FEP患者,他们的父母,兄弟姐妹和对照组之间的PS子组件的性能差异.
- 在这些群体中探索PS运动和认知因素之间的结构关系.
主要方法:
- 使用了从Trail Making Test A/B,数字符号编码,槽板和Stroop子测试中的数据.
- 在控制中使用探索性因素分析 (EFA) 来定义PS结构.
- 应用确认因素分析 (CFA) 以验证FEP患者,父母和兄弟姐妹的结构.
主要成果:
- EFA确定了一个双因素模型:运动 (因素1) 和认知 (因素2) 子组件.
- CFA证实了所有组的这种结构,揭示了因子间关系的显著差异.
结论:
- 因素关系的变化表明FEP患者,亲属和对照者采用了不同的补偿机制.
- 这些发现提供了 PS 缺陷在精神病和家族风险的神经生物学基础的见解.
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