公民身份对获得儿科肝脏和脏移植的机会的影响
Donna C Koo1, P Nina Scalise1, Megan Z Chiu1
1Department of Surgery, Boston Children's Hospital, Boston, Massachusetts, USA.
概括
儿科非美国公民居民 (PNCR) 占肝脏和脏移植接受者的很小一部分. 尽管国家趋势稳定,但PNCR移植活动的显著区域差异表明可访问性障碍.
科学领域:
- 器官移植 器官移植 器官移植
- 儿科病学 儿科病学
- 儿科肝病学 儿科肝病学
背景情况:
- 对于非美国公民居民来说,移植是一个敏感的问题.
- 了解儿科非公民居民 (PNCR) 中的器官移植活动至关重要.
研究的目的:
- 评估PNCR中肝脏和脏移植活动的国家趋势.
- 为了确定PNCR移植率的地理差异.
主要方法:
- 利用了来自器官采购和移植网络和移植受体科学注册 (2012-2022) 的数据.
- 分析了儿童肝脏和脏接受者等候名单的增加,移植手术和公民身份状况.
- 将PNCR移植率与美国人口普查局的人口数据进行比较.
主要成果:
- PNCR占儿科肝脏新增病例的1.5%,脏新增病例的3.3%.
- 在儿童肝脏移植中,PNCR占1.5%,移植中占2.9%.
- 没有观察到PNCR移植活动的全国性显著变化.
- 在PNCR等候名单的增加和移植中,在UNOS地区发现了显著的地理差异.
结论:
- 这项研究提供了PNCR移植活动的首次全国性分析.
- 显著的区域差异表明,有潜在的系统性和结构性障碍阻碍了PNCR移植的机会.
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