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Updated: Jun 23, 2025

The Soft Agar Colony Formation Assay
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SENP2-NDR2-p21轴调节肺癌细胞的生长

Yixuan Cheng1, Wanxin Hou2, Houshun Fang3

  • 1Institute of Traditional Chinese Medicine Surgery, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China; Longhua Clinical Medical College, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

European journal of pharmacology
|June 22, 2024
PubMed
概括

森特林/小型泛素类修饰剂 (SUMO) 特定蛋白酶2 (SENP2) 通过调节NDR2激酶活性和p21稳定性来驱动肺癌的生长. 甲酸IV抑制了这种途径,提供了潜在的肺癌治疗方法.

关键词:
阿斯特拉加洛西德IV细胞循环的细胞周期肺癌是一种肺癌.在 NDR2/STK38L 中.这就是SENP2的意义.

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