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Updated: Jun 23, 2025

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苏尔M的产生单巴克坦的铁酶域的结构与上游载体蛋白质域形成了一个独特的复合体

Ketan D Patel1, Ryan A Oliver2, Michael S Lichstrahl2

  • 1Department of Structural Biology, University at Buffalo, SUNY, Buffalo, New York, USA.

The Journal of biological chemistry
|June 22, 2024
PubMed
概括

非核糖体合成酶 (NRPSs) 产生生物活性. 研究人员结构性地分析了一个关键的铁酶域,揭示了对不寻常的β-乳酸形成的洞察力,并使得新的抗生素基因集群的发现成为可能.

关键词:
在此之前,NRPS是NRPS.抗生素 抗生素是一种抗生素.莫诺巴克坦 (Monobactam) 是一种药物.自然产品的生物合成.非核糖体合成酶非核糖体合成酶蛋白质的结构/功能.铁酶酶的使用方法这是一种β-lactam抗生素.

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