OSA类型III和神经认知功能
Brigitte Fauroux1, Mathilde Cozzo2, Joanna MacLean3
1Pediatric Noninvasive Ventilation And Sleep Unit, AP-HP, Hôpital Necker Enfants Malades, Paris, France; EA 7330 VIFASOM (Vigilance Fatigue Sommeil et Santé Publique), Paris University, Paris, France.
Paediatric respiratory reviews
|June 22, 2024
概括
患有阻塞性睡眠呼吸暂停 (OSA) 的儿童由于腺/桃体扩大,往往有神经认知和行为问题. 对这些高风险儿童来说,早期评估睡眠和认知能力至关重要.
科学领域:
- 儿科肺病学 儿科肺病学
- 神经发育儿科 神经发育儿科
- 睡眠医学 睡眠医学
背景情况:
- 儿童的阻塞性睡眠呼吸暂停 (OSA),特别是那些上呼吸道异常 (OSA III型) 的儿童,与神经认知功能障碍和行为问题有关.
- 这些儿童面临更严重的OSA风险更高,但其神经认知影响尚未得到充分研究.
- 查,睡眠研究和测试方面的挑战使得这种特定人群的研究复杂化.
研究的目的:
- 为了研究上呼吸道异常的儿童中OSA的神经认知后果.
- 为了突出这一脆弱群体中OSA,睡眠障碍和行为问题之间的关联.
- 强调需要对睡眠和神经认知功能进行早期和系统的评估.
主要方法:
- 对现有研究的审查,重点关注患有OSA型III的儿童,包括患有唐氏综合征的儿童.
- 分析OSA严重程度,睡眠架构障碍和神经认知/行为结果之间的关系.
- 探索在这一群体中诊断和评估OSA的挑战.
主要成果:
- 研究表明,OSA,甚至更是睡眠架构和睡眠质量不佳的睡眠,加剧神经认知障碍和行为异常.
- 患有OSA类型III的儿童经历了显著的神经认知缺陷和行为问题.
- 潜在疾病和诊断挑战的复杂性有助于低估OSA的影响.
结论:
- 在患上上呼吸道异常的儿童中,OSA显著影响神经认知功能和行为.
- 睡眠质量和结构的破坏在加剧这些障碍方面起着至关重要的作用.
- 对睡眠,神经认知功能和行为进行系统的早期评估对于患有OSA型III的儿童至关重要.
关键词:
我们的行为行为.功能上呼吸道异常 功能上呼吸道异常遗传性疾病是一种遗传性疾病.神经认知功能 神经认知功能阻塞性睡眠呼吸暂停 阻塞性睡眠暂停睡眠质量 睡眠质量睡眠呼吸障碍 睡眠呼吸障碍 睡眠呼吸障碍更多相关视频
07:43Immunohistochemical Visualization of Hippocampal Neuron Activity After Spatial Learning in a Mouse Model of Neurodevelopmental Disorders
Published on: May 12, 2015
11.3K
06:46Automated, Long-term Behavioral Assay for Cognitive Functions in Multiple Genetic Models of Alzheimer's Disease, Using IntelliCage
Published on: August 4, 2018
12.1K
相关概念视频
01:26Alzheimer's Disease: Overview
462
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
462
01:28Disorders of the Nervous Tissue
1.1K
Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
1.1K
01:22Cranial Nerves: Types Part II
2.4K
Cranial nerves are responsible for transmitting motor and sensory information between the brain and various parts of the body. There are twelve pairs of cranial nerves. While the first six innervate the head and neck, the latter six nerves innervate the head and neck, as well as organs and tissues in the thoracic and abdominal cavities. They facilitate communication, expression, and autonomic control within the human body.
Facial Nerve (Cranial Nerve VII)
Cranial nerve VII, or the facial nerve,...
Facial Nerve (Cranial Nerve VII)
Cranial nerve VII, or the facial nerve,...
2.4K
01:37Neural Regulation
39.3K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
39.3K
01:27Language and Cognition
342
Language serves as a bridge between ideas and communication, influencing how individuals perceive and interact with the world. Psychologists have long debated whether language shapes thought or vice versa. This discussion gained grip with Edward Sapir and Benjamin Lee Whorf in the 1940s, who proposed that language determines thought, a concept known as linguistic determinism. They suggested that the vocabulary and structure of a language influence how its speakers think and perceive reality.
342
01:22Alzheimer's Disease: Treatment
179
Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
179