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Updated: Jun 23, 2025

Visualization of DNA Repair Proteins Interaction by Immunofluorescence
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在DNA双链断裂修复蛋白的广泛的染色体上下文依赖性

Xabier Vergara1,2,3,4, Anna G Manjón3,4, Marcel de Haas1,2,4

  • 1Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands.

Nature communications
|June 22, 2024
PubMed
概括

像非同源端结合 (NHEJ) 和微同源介导端结合 (MMEJ) 这样的DNA修复途径受到染色质上下文的影响. 这项研究确定了调节NHEJ和MMEJ之间的平衡的蛋白质,基于它们的局部染色质环境.

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