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Updated: Jun 23, 2025

In Vivo Inhibition of MicroRNA to Decrease Tumor Growth in Mice
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KLHL14是一种瘤抑制剂,在未分化甲状腺癌中降低调控

Matteo Esposito1,2, Antonella Migliaccio1, Sara Carmela Credendino1

  • 1Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), Università degli Studi di Napoli Federico II, Via Pansini 5, 80131, Napoli, Italy.

Cell death discovery
|June 22, 2024
PubMed
概括

凯尔奇样蛋白14 (KLHL14) 在甲状腺癌中起到瘤抑制作用,减少表达与侵略性,不分化的瘤有关. 恢复KLHL14抑制癌细胞生长并促进细胞亡,突出显示其在甲状腺细胞分化中的作用.

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