多中心和多模式成像研究揭示了SARS-CoV-2感染后患者罕见的 fundus 病变
Guangqi An1,2, Bo Lei3,4, Zhili Wang3
1Department of Ophthalmology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Scientific reports
|June 22, 2024
概括
SARS-CoV-2 感染可以导致各种眼睛问题,主要是年轻女性的急性黄斑神经红斑病 (AMN). 多式成像显示AMN是最常见的底部发现,与其他罕见的条件.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 视网膜成像 视网膜成像
背景情况:
- SARS-CoV-2 感染与各种系统性和眼部并发症有关.
- 在COVID-19之后的 fundus表现需要使用先进的成像进行详细的表征.
研究的目的:
- 在SARS-CoV-2感染后出现视觉投诉的患者中定义底部异常的谱.
- 评估多式成像在诊断这些后感染性眼部疾病的实用性.
主要方法:
- 追溯性多中心研究,涉及90名在SARS-CoV-2感染后出现视觉症状的患者.
- 采用了多式成像技术,包括光连贯断层扫描和红外网膜摄影.
- 记录了人口统计数据和感染与视觉症状之间的时间关系.
主要成果:
- 在86.66%的患者中诊断出急性黄斑神经联结症 (AMN),主要是年轻女性,通常是双边的.
- 在24.36%受影响的眼睛中观察到Purtscher或Purtscher类病变.
- 其他确定的疾病包括普尔茨赫视网膜病变,Vogt‒Koyanagi‒Harada (VKH) 综合征或VKH类脑膜炎,MEWDS和ROCM.
结论:
- SARS-CoV-2 感染可以导致一系列 fundus 病理.
- AMN是最常见的眼部发现,多式成像有效地可视化这些病变.
- 眼科医生应考虑COVID-19后视力障碍患者的各种 fundus 症状.
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