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Updated: Jun 23, 2025

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在急性髓性白血病前体细胞中,在应激反应期间调节WTAP和m6A修饰的circRNAs

Alessia Iaiza1, Gilla Mazzanti2, Frauke Goeman3

  • 1Department of Biology and Biotechnology 'Charles Darwin', Sapienza University of Rome, P.le Aldo Moro, 5, 00185, Rome, Italy.

Cellular and molecular life sciences : CMLS
|June 23, 2024
PubMed
概括

在急性髓性白血病 (AML) 细胞中,博尔特佐米布治疗对N6 - 甲基亚丁素 (m6A) RNA调节和循环RNA (circRNA) 表达产生影响,揭示了潜在的治疗点. 这种蛋白质毒性应激反应会影响氧化应激和蛋白质平衡.

关键词:
在AML,AML就是AML.氧化应激是一种氧化应激.在WTAP中,使用的是WTAP.在 circHIPK3K3中使用.环绕RNAss 的时间.m6A 一个很好的.

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