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Updated: Jun 23, 2025

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291
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Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291

Published on: December 10, 2016

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循环 diguanylate 差异调节了Clostridioides difficile中毒性因子和致病相关表型的表达

Zirou Ouyang1, Min Zhao1, Jiayiren Li1

  • 1Hebei Provincial Center for Clinical Laboratories, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.

Microbiological research
|June 23, 2024
PubMed
概括

周期性迪加尼酸盐 (c-di-GMP) 调节了Clostridioides difficile感染 (CDI) 的毒性. 高水平的c-di-GMP抑制了子,毒素和鞭毛的产生,但促进了IV型 pili和生物膜的形成,为CDI提供了新的治疗点.

关键词:
在C-di-GMP中克洛斯特里迪奥伊德斯困难菌致病性 致病性 致病性病毒性因素是病毒性因素.

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