食中酸盐可以减少通过肠道微生物群的脂肪沉积和 brojlers 的脂质代谢
Fang Wang1, Jiaqi Feng1, Min Yao2
1College of Animal Science and Technology, Shihezi University, Shihezi, Xinjiang 832000, China.
Poultry science
|June 23, 2024
概括
0.4%的酸盐补充剂通过改善脂质代谢和改变肠道微生物群,有效地降低了 brojlers 的脂肪积累. 这项研究确定了肉料中酸盐的最佳饮食水平.
科学领域:
- 动物营养和新陈代谢
- 禽畜科学 禽畜科学 禽畜科学
- 生物化学 生物化学
背景情况:
- 苏酸是一种具有已知的生理功能的营养补充剂.
- 苏酸盐对的脂质代谢的影响仍然未被探索.
- 了解酸盐的作用对于优化肉生长和健康至关重要.
研究的目的:
- 调查糖酸盐补充剂对 brojlers 脂肪沉积的影响.
- 阐明酸盐对脂质代谢的影响的潜在机制.
- 为了确定牛肉的最佳食糖酸盐水平.
主要方法:
- 640只雄性黄羽肉被分为四组 (对照组和三种酸盐水平:0.2%,0.4%,0.6%) 持续21天.
- 对料摄入量,血清代谢物,腹部脂肪,基因表达 (脂生和脂解),发酵,肠道微生物群 (16S rRNA测序) 和代谢学 (LC-MS) 的评价影响.
- 分析了酸盐的线性和二次效应.
主要成果:
- 0.4%的酸盐补充剂降低了平均每日料摄入量,血清甘油三和葡萄糖,同时增加了高密度脂蛋白胆固醇.
- 它降低了腹部脂肪百分比,脂肪细胞大小和脂质基因表达,同时上调肝脏和脂肪中的脂质基因表达.
- 0.4%的酸盐增加了酸,改变了肠道微生物群的组成 (增加了Blautia和Sellimonas),并丰富了与氨基酸相关的代谢途径.
结论:
- 在 brojlers中补充糖酸盐的最佳饮食水平被确定为0.4%.
- 酸盐通过调节肠道菌群并影响与脂质代谢相关的氨基酸代谢,有效地减少脂肪积累.
- 苏酸盐显示出作为料添加剂的潜力,可以改善脂质代谢并减少 brojlers中的脂肪沉积.
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