教育:2023年的紧急医疗药物治疗文献
Jennifer Koehl1, Caitlin S Brown2, Brett Faine3
1Department of Pharmacy, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.
The American journal of emergency medicine
|June 23, 2024
概括
本综述强调了2023年紧急医疗 (EM) 药物治疗的关键文献,重点关注重症监护,毒理学和创伤. 它涵盖了紧急医疗药物治疗中的最新指导方针和有争议的话题.
科学领域:
- 紧急医疗 紧急医疗
- 临床药理学 临床药理学
- 基于证据的医学基于证据的医学.
背景情况:
- 紧急医疗药物治疗的景观正在不断发展.
- 保持最新的研究和指导方针对于最佳的患者护理至关重要.
- 最近进展的全面摘要有助于临床决策.
研究的目的:
- 综合和批判性地评估2023年出版的紧急医学的高影响力药理疗文献.
- 为所选研究,指南和元分析的临床相关性提供评论.
- 解决紧急医疗药物管理中的持续争议和新兴趋势.
主要方法:
- 在2023年索引的预先确定期刊的文献搜索.
- 修改的Delphi方法用于文章选择.
- 建议评级,评估,发展和评估 (GRADE) 系统 (GRADE 1A和1B) 用于评估证据质量.
- 专家审查和对选定的出版物进行集体讨论.
主要成果:
- 13篇文章的摘要和评论,6条指导方针和5个元分析.
- 关键主题包括快速序列输管,心脏骤停管理,中毒毒性,创伤相关出血,液体复苏,缺血性中风治疗和肺炎管理.
- 讨论血液制品的使用和类固醇使用中的争议.
结论:
- 经过审查的文献提供了关于紧急医疗药物药理疗的关键更新和见解.
- 证据支持快速序列输管和关键病情管理的最新指南.
- 正在进行的辩论突出了未来研究和临床实践改进的领域.
更多相关视频
11:17Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
12.9K
07:58Behavioral and Network Pharmacology-Based Analyses for the Traditional Mongolian Medicine Zadi-5 in a Rat Model of Depression
Published on: February 24, 2023
501
相关概念视频
01:18Drug Delivery: Enteral Route
417
The enteral drug administration involves three primary routes: oral, sublingual, and buccal. Oral ingestion is the most prevalent, safe, economical, and convenient method for drug administration. However, it has certain drawbacks, including limited absorption due to the drug's low water solubility or poor membrane permeability, possible emesis from GI mucosa irritation, destruction of drugs by digestive enzymes or low gastric pH, and irregular absorption along with food or other drugs.
417
01:02Prescription, Nonprescription and Orphan Drugs
719
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
719
01:28Drug Therapy
42
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
42
01:19Pharmacovigilance
821
Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
821
01:21Pharmacodynamics: Overview and Principles
1.1K
Pharmacodynamics is a scientific field that delves into drugs' intricate biochemical, cellular, and physiological effects on the human body. The study of pharmacodynamics helps us understand how drugs interact with the body and elicit various responses.
Most drugs' effects result from their interactions with drug receptors or targets within the body. These interactions trigger specific responses at the cellular or systemic level. Drug receptors can be found on the surfaces of cells or...
Most drugs' effects result from their interactions with drug receptors or targets within the body. These interactions trigger specific responses at the cellular or systemic level. Drug receptors can be found on the surfaces of cells or...
1.1K
01:20Pharmacokinetic Models: Overview
648
Pharmacokinetic models utilize mathematical analysis to achieve a detailed quantitative understanding of a drug's life cycle within the body. They are instrumental in simulating a drug's pharmacokinetic parameters, predicting drug concentrations over time, optimizing dosage regimens, linking concentrations with pharmacologic activity, and estimating potential toxicity.
There are three primary types of models: empirical, compartment, and physiological. Empirical models, with minimal...
There are three primary types of models: empirical, compartment, and physiological. Empirical models, with minimal...
648