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Ekaterina V Radyuk¹, Natalia V Breneva², Sofia E Budaeva²

¹Central Research Institute of Epidemiology, 111123 Moscow, Russia.

|June 23, 2024

概括

在越南蝙蝠中发现了致病性Leptospira DNA,在许多物种中检测到了特定的抗体. 这突出了蝙蝠作为Leptospira传播的潜在储库.

科学领域:

兽医微生物学兽医微生物学
动物传染病研究研究
野生动物流行病学

背景情况:

蝙蝠越来越多地被认为是各种动物传染病原体的储.
斑螺杆菌引起的动物性疾病 - - 斑螺杆菌 - - 构成了严重的公共卫生问题.
了解野生动物群体中的病原体存在对于预防疾病至关重要.

研究的目的:

在越南的蝙蝠种群中调查致病性Leptospira和相关抗体的患病率.
为了确定庇护莱普托斯皮拉的蝙蝠物种,并描述检测到的菌株的遗传多样性.
评估蝙蝠在该地区白病流行病学中的作用.

主要方法:

实时聚合酶连锁反应 (PCR) 用于检测蝙蝠组织样本中的Leptospiral DNA.
与酶相关的免疫吸收试验 (ELISA) 和微观聚合试验 (MAT) 用于检测抗莱普托斯皮拉抗体.
对 secY 基因进行了遗传学分析,以确定 Leptospira 种类和血统.

主要成果:

在5个物种中,在298只蝙蝠中,有40只 (13.4%) 检测到Leptospiral DNA,其中Rousettus amplexicaudatus (55.5%) 和Rousettus leschenaultii (40.4%) 的流行率最高.
遗传学分析揭示了莱普托斯皮拉博格佩特塞尼,L. kirshneri以及与L. noguchii/L. noguchii相关的新型血统. 询问者. 询问者. 询问者. 这是一个问题.
在306只蝙蝠中的83只 (27.1%) 通过ELISA检测发现了抗勒普托斯皮拉抗体,其中41只通过MAT确认阳性. 主要的血清组是塔拉索维和米尼.

结论:

越南的蝙蝠携带致病性Leptospira,这表明它们的作用是潜在的水库.
在蝙蝠中发现的LeptoSpira的遗传多样性表明复杂的传播动态.
这些发现强调了蝙蝠监测对于白病预防和控制策略的重要性.

关键词:

蝙蝠蝙蝠蝙蝠蝙蝠在艾丽莎·伊丽莎·伊丽莎莱普托斯皮拉 (Leptospira) 是一个类动物.微观聚合试验微观聚合试验这是一个PCRPCR.

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