在麻醉过程中对马子宫内膜微生物组的metagenomic表征
B A Heil1, M van Heule2, S K Thompson3
1Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, 70803, USA; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, WA, 99164, USA.
Journal of equine veterinary science
|June 23, 2024
概括
马的子宫微生物组在雌激和无激之间存在显著差异. 雌激素表现出较低的微生物多样性和丰富性,而麻醉菌表现出更高的多样性,影响马的生殖健康.
科学领域:
- 生殖生物学 生殖生物学
- 微生物组研究的研究.
- 马科的科学 马科的科学
背景情况:
- 马子宫对于繁殖至关重要,研究通常集中在雌激素水平高的雌激素阶段.
- 众所周知,马的阴道微生物组在整个雌性周期内是稳定的,但子宫微生物组对周期性的反应仍然不清楚.
研究的目的:
- 在麻醉期间描述健康母马的子宫内膜微生物组.
- 为了比较马的子宫内膜微生物组在麻醉期间与在雌激.
主要方法:
- 从雌雄 (n=16) 和麻醉 (n=8) 的母马中采集了双护护子子宫内膜拭子.
- 使用16S rRNA测序确定了微生物种群.
主要成果:
- 与anestrus相比,雌激素中的马子宫微生物组表现出较低的多样性和丰富性.
- 雌性菌和性菌的子宫内膜微生物组主要由蛋白质菌,细菌菌和细菌菌组成.
- 在麻醉和期之间的微生物社区组成中观察到显著的差异.
结论:
- 马子宫内膜微生物组的组成随着雌激周期的变化而有显著变化.
- 这些变化可能与不同周期阶段子宫内膜免疫环境的变化有关.
- 需要进一步研究马类子宫内膜微生物组的功能和动态变化.
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