在移植和细胞治疗领域应用实施科学
Anna M DeSalvo1, Stephen R Spellman1, Jennifer A Sees Coles1
1CIBMTR® (Center for International Blood and Marrow Transplant Research), NMDP, Minneapolis, Minnesota.
Transplantation and cellular therapy
|June 23, 2024
概括
实施科学 (IS) 弥合了血液细胞移植和细胞疗法 (HCT/CT) 的研究和实践之间的差距. 应用IS确保基于证据的实践能够覆盖所有患者,通过协作和可持续性改善健康结果.
科学领域:
- 医疗保健服务研究 医疗服务研究
- 翻译科学 翻译科学
- 在医疗保健中的实施科学.
背景情况:
- 实施科学 (IS) 系统地促进采用基于证据的实践.
- 研究结果和临床实践之间存在很大的差距,影响患者的治疗结果.
- 血造细胞移植和细胞疗法 (HCT/CT) 可以从结构化的实施策略中受益.
研究的目的:
- 阐明IS在HCT/CT中的作用和应用.
- 区分IS与临床研究和质量改进.
- 突出IS战略,以提高医疗公平性和HCT/CT患者的治疗结果.
主要方法:
- 审查IS原则及其对HCT/CT的相关性.
- 将IS与临床研究和质量改进方法的比较.
- 国际血液和骨髓移植研究中心 (CIBMTR) 的IS应用案例.
主要成果:
- IS提供了一个框架,将HCT/CT研究转化为实践.
- 信息系统有助于分析当前的做法,并制定有针对性的干预措施.
- CIBMTR使用IS进行传播,评估,扩展和可持续性.
结论:
- 信息化对于最大限度地提高HCT/CT研究对患者护理的影响至关重要.
- 合作方法和对基于证据的实践的承诺是成功IS的关键.
- 通过IS的应用,可以改善HCT/CT的健康公平性和标准化最佳实践.
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