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Oral Health Assessment by Lay Personnel for Older Adults
Published on: February 2, 2020
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口腔恶臭与痴呆症之间的关联:在日本进行了为期11年的随访研究
Duc Sy Minh Ho1,2, Takashi Zaitsu1, Hikaru Ihira3
1Department of Oral Health Promotion, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Journal of Alzheimer's disease reports
|June 24, 2024
概括
口臭或口腔恶臭显著增加痴呆症的风险. 这项研究发现,患有严重口腔恶臭的人患痴呆症的风险高3.8倍,这突显了口腔健康和认知能力下降之间的关键联系.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
背景情况:
- 不频繁的社交互动是已知的痴呆症风险因素.
- 口腔恶臭可能导致社会隔离,可能增加痴呆症风险.
- 阿尔茨海默氏症是一种常见的痴呆症.
研究的目的:
- 调查口腔恶臭与痴呆症发病之间的关联.
- 量化与不同程度的口腔恶臭相关的痴呆风险.
主要方法:
- 利用来自日本公共卫生中心的前性研究的数据.
- 包括1493名56至75岁的参与者进行牙科检查和调查.
- 使用长期护理保险数据 (2006-2016) 对痴呆症发病的参与者进行了跟踪.
- 采用了考克斯的比例危险模型和反向概率加权的考克斯模型进行分析.
主要成果:
- 6.4%的参与者在15274个人年内患上了痴呆症.
- 患有严重口腔恶臭的参与者患有痴呆症的发病率最高 (1000人年中有22.4人).
- 严重的口腔恶臭与调整混因子后,痴呆发作的风险增加了3.8倍.
结论:
- 口腔恶臭和痴呆症发病之间存在显著的关联.
- 口腔恶臭代表了痴呆的潜在可修改的风险因素.
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