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Updated: Jun 23, 2025

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大型语言模型可以预测抗微生物的活性和毒性吗?

Markus Orsi1, Jean-Louis Reymond1

  • 1Department of Chemistry, Biochemistry and Pharmaceutical Sciences, University of Bern Freiestrasse 3 3012 Bern Switzerland jean-louis.reymond@unibe.ch.

RSC medicinal chemistry
|June 24, 2024
PubMed
概括

大型语言模型显示了预测抗微生物 (AMP) 活性和毒性的潜力. 然而,像RNN和SVM这样的更简单的模型目前为AMP开发提供了更可靠的预测.

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Antimicrobial Proteins01:23

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Antimicrobial proteins are important components of the immune system. They aid the body in combating pathogens by either killing them directly or hindering their replication processes. Four main types of antimicrobial substances are interferons, the complement system, iron-binding proteins, and antimicrobial proteins.
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
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