相关实验视频

Updated: Jun 23, 2025

In Vivo Evaluation of the Mechanical and Viscoelastic Properties of the Rat Tongue

In Vivo Evaluation of the Mechanical and Viscoelastic Properties of the Rat Tongue

Published on: July 6, 2017

难以入睡与单侧下神经刺激中较差的治疗结果有关

Johannes Pordzik¹, Katja Petrowski², Katharina Ludwig¹

¹Department of Otolaryngology, Head and Neck Surgery & Sleep Medicine Center, University Medical Center Mainz, Mainz, 55131, Germany.

Nature and science of sleep

|June 24, 2024

概括

难以入睡会对阻塞性睡眠呼吸暂停 (OSA) 的低分泌神经刺激 (HGNS) 治疗产生负面影响. 术前失眠评估对于优化OSA患者的HGNS治疗结果至关重要.

科学领域:

睡眠医学睡眠医学
神经调节是一种神经调节.
呼吸系统医学呼吸系统医学

背景情况:

阻塞性睡眠呼吸暂停 (OSA) 和失眠经常同时存在,使治疗复杂化.
低分泌神经刺激 (HGNS) 是OSA的公认的二线治疗方法.
关于失眠方面如何影响HGNS治疗疗效的研究有限.

研究的目的:

调查失眠症状对OSA患者HGNS治疗结果的影响.
在临床环境中分析特定失眠方面与HGNS治疗有效性之间的相关性.

主要方法:

对30名用HGNS.治疗的OSA患者的回顾性分析.
手术前和后续的多睡眠图 (PSG) 来评估呼吸暂停-呼吸暂停指数 (AHI) 和氧气脱度指数 (ODI).
失眠严重程度指数 (ISI) 调查问卷用于失眠评估;计算了斯皮尔曼的rho相关性.

主要成果:

在第二次随访时发现睡眠困难 (ISI项目1) 与AHI和ODI的改善之间存在显著的负相关性.
手术前的ISI分数表明不眠症的严重程度中等.
HGNS治疗显示AHI和ODI的减少,但结果各不相同.

结论:

难以开始睡眠可能会损害HGNS对OSA的治疗效果.
在HGNS治疗中,建议对失眠症状进行手术前评估,以选择和治疗患者.
需要进行进一步的研究,以探索在接受HGNS的OSA患者失眠的有针对性的干预措施.

关键词:

低分泌神经刺激的低分泌神经刺激失眠是因为失眠.阻塞性睡眠呼吸暂停 (SOP) 的情况.聚类人体图像 (polysomnography) 是一种多人体图像.

更多相关视频

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression

Published on: January 7, 2019

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

相关概念视频

Management of Insomnia

Management of Insomnia

The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...

Sleep-Wake Cycles

Sleep-Wake Cycles

Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:

Sedatives and Hypnotics Drugs: Miscellaneous Agents

Sedatives and Hypnotics Drugs: Miscellaneous Agents

Sedatives and hypnotics encompass a wide range of substances, each with its unique mechanism of action, uses, and potential adverse effects.
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...