查癌性心脏病:趋势和未来前景
Bryan Mouser1, James R Howe2, Olivia Atari1
1University of Iowa Hospitals and Clinics Department of Cardiothoracic Surgery, Iowa City, IA, USA.
概括
自从专家指南发表以来,神经内分泌瘤 (NET) 患者的癌症性心脏病 (CHD) 查得到了改进. 使用NANETS标准增加了心声图查,有助于早期发现心血管疾病,特别是在高危患者中.
科学领域:
- 心脏病学 心脏病学
- 在瘤学瘤学.
- 医学指导方针 医学指导方针
背景情况:
- 从历史上看,查癌性心脏病 (CHD) 缺乏专家指导方针.
- 北美神经内分泌瘤学会 (NANETS) 在2017年发布了关于神经内分泌瘤 (NET) 患者心血管疾病查的建议.
- 这项研究评估了二十年来在第三级护理中心的CHD查趋势和指导方针的实用性.
研究的目的:
- 评估NANETS专家建议对心血管疾病查实践的影响.
- 评估20多年来CHD查的趋势.
- 确定在NET患者中针对CHD的特定查标准的有用性.
主要方法:
- 进行手术评估的334名NET患者的回顾性审查.
- 从1999-2018年和2021-2022年收集的数据.
- 记录的实验室值和临床特征与NANETS标准相比:肝转移,血清素水平,NT-ProBNP和临床CHD症状.
主要成果:
- 85%的患者符合至少一个NANETS查标准.
- 只有40%的符合条件的患者接受了心声图查.
- 在第一个和第二个十年之间,查率从32%增加到40.6%,在指南发布后增加到70%.
- 具有多个标准的患者更有可能患有结构膜疾病.
结论:
- 实施NANETS推的查标准显著增加了回声心电图用于心脏病查的使用率.
- 这些标准可以帮助在NET患者中早期发现CHD.
- 符合多个查标准的患者患结构病的可能性更高,这凸显了全面查的重要性.
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