在演讲中,Pars Opercularis 支着不同的预测和成功的听觉反处理:来自左半球中风的证据
Sara D Beach1, Ding-Lan Tang1,2, Swathi Kiran3
1Waisman Center, The University of Wisconsin-Madison.
Neurobiology of language (Cambridge, Mass.)
|June 24, 2024
概括
患有失言症 (PWA) 的人可以检测和纠正语音错误,展示完整的听觉反处理. 在PWA中保存的神经抑制和行为纠正突出了左半球运动规划对语音准确性的重要性.
科学领域:
- 神经科学是一个神经科学.
- 语音科学 语言科学
- 阿法西亚研究研究
背景情况:
- 语音的实时声学自我监测依赖于将左半球运动规划区域的不同预测与感官反进行比较.
- 感官预测错误对于检测偏差语音声音和启动在线语音控制的纠正行动至关重要.
研究的目的:
- 调查左半球损伤的口音障碍 (PWA) 患者的语音检测-校正电路的完整性.
- 为了确定PWA是否能够保持在线控制语音声学,尽管语音输出可变性的潜在缺陷.
主要方法:
- 磁脑电图 (MEG) 用于记录15个PWA和年龄匹配的对照中的神经活动在语音产生和听觉反期间.
- 测量了发言诱导的M100神经反应抑制,并与病变形状和语音行为相关联.
- 对声学偏差的皮质敏感性被评估与神经和行为措施相关.
主要成果:
- 在群体层面,PWA表现出保留的说话诱导的神经抑制和皮质对语言偏差的皮质敏感性.
- 在PWA中更大程度地保存了骨骨,与左半球神经抑制的增加以及对偏差语音的行为纠正的增强相关.
- 在表现出更大的行为纠正的失语个体在任务期间表现出更少的明显语言错误.
结论:
- 这些发现表明,尽管左半球病变,但用于检测和纠正语音错误的神经机制在PWA中基本上完好无损.
- 左半球运动规划区域对于生成预测和执行当听觉反违反这些预测时的纠正至关重要.
- 有效预测机制的完整性对于有效在线控制语音声学和最大限度地减少PWA中的语音错误至关重要.
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