乳腺癌免疫疗法:整形外科医生的临床审查
Matthew J Heron1, Katherine J Zhu1, Lily Zhu1
1From the Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, Md.
Plastic and reconstructive surgery. Global open
|June 24, 2024
概括
乳腺癌免疫疗法具有特定的副作用. 术前评估应根据个体患者的治疗方案进行,同时考虑与不同药物相关的心脏毒性和甲状腺功能低下等风险.
科学领域:
- 在瘤学瘤学.
- 免疫学 免疫学 免疫学
- 药理学 药理学是指药理学的学科.
背景情况:
- 免疫疗法彻底改变了乳腺癌的治疗方法.
- 管理免疫疗法不良事件和外科手术期间的考虑提出了挑战.
研究的目的:
- 为了确定FDA批准的乳腺癌免疫疗法.
- 总结不良事件,禁忌和术前建议.
主要方法:
- 利用FDALabel寻找已批准的乳腺癌免疫疗法.
- 从包装插件中提取了关于警告,预防措施,指示和不良事件的数据.
主要成果:
- 在三个类别中确定了九种免疫疗法:抗HER2,抗PD-1和抗TROP-2.
- 常见的不良事件包括心脏毒性 (抗HER2),甲状腺功能低下 (抗PD-1),腹和中性质衰竭 (抗TROP-2).
- 推的手术前评估:心声回声,肝功能测试,甲状腺面板,以及对静脉瘤,血瘤和感染风险的评估.
结论:
- 建议根据特定的免疫疗法方案进行量身定制的手术前评估.
- 这种方法旨在优化患者的安全性和乳腺癌免疫治疗的结果.
相关概念视频
01:27Tumor Immunotherapy
511
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
511
01:30Cancer Vaccines
352
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
352
02:49Cancer Therapies
7.6K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.6K
02:57Targeted Cancer Therapies
7.5K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.5K