在肯尼亚蒙巴萨服用甲的阿片类药物依赖客户中,治疗结果差的危险因素
Nassoro Mwanyalu1, Maria Nunga2, Raphael Mwanyamawi1
1Department of Health Service, Mombasa County, Mombasa, Kenya.
Advances in drug and alcohol research
|June 24, 2024
概括
肯尼亚的甲维持治疗 (MMT) 显示,失业,缺乏教育和不注射药物与较差的结果有关. 建议对这些患者进行更密切的监测,以更好地维持治疗.
科学领域:
- 公共卫生 公共卫生
- 成 药物 药物 药物 药物
- 传染性疾病 传染性疾病
背景情况:
- 甲维持治疗 (MMT) 有效地减少非法阿片类药物使用,改善艾滋病毒治疗结果.
- 关于影响肯尼亚MMT保留和结果的因素的数据有限.
- 这项研究调查了肯尼亚蒙巴萨治疗不良结果的决定因素.
研究的目的:
- 在蒙巴萨MMT计划中,确定与阿片类药物依赖个体中不良治疗结果相关的因素.
- 为提高MMT计划有效性提供有针对性的干预信息.
主要方法:
- 从2017-2019年对443名MMT患者的回顾性记录审查.
- 定义了糟糕的结果,如丢失后续 (LTFU),新的艾滋病毒/病毒性肝炎诊断或错过的抗逆转录病毒疗法 (ART) 预约.
- 分析了社会人口统计学,临床病史和风险因素,使用流行几率比率 (POR) 和95%信心区间 (CI).
主要成果:
- 整体不良结局率为27.5%,LTFU为22.8%.
- 缺乏正规教育 (POR:2.7),失业 (POR:2.4) 和非注射者 (POR:1.7) 显著与治疗的不良保留有关.
- 女性客户更年轻,更受过教育,艾滋病毒和HCV的流行率更高.
结论:
- 失业,缺乏正规教育和非注射者身份是肯尼亚人口中MMT结果差的关键预测因素.
- 建议在MMT中加强综合护理诊所 (CCC) 服务的监测和整合,以帮助处于危险的个人.
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