对患者的药理管理和潜在不适当的处方
Luis Fernando Valladales-Restrepo1,2, Laura Sofia Serna-Echeverri1, Juan Darío Franco-Ramírez1
1Drs. Valladales-Restrepo, Serna-Echeverri, Franco-Ramírez, and Machado-Alba are with the Grupo de Investigación en Farmacoepidemiologia y Farmacovigilancia at the Universidad Tecnológica de Pereira-Audifarma SA in Pereira, Colombia.
The Journal of clinical and aesthetic dermatology
|June 24, 2024
概括
患者经常接受不适当的药物,特别是全身抗生素,这可能会使皮肤病变恶化. 这项研究发现,近五分之一的患者被处方可能有害的药物,突出需要更好的处方实践.
科学领域:
- 皮肤病学 皮肤病学
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
背景情况:
- 是一种常见的慢性炎症性皮肤疾病,影响着pilosebaceous单位.
- 目前的治疗包括局部和全身药物,但有些药物可以矛盾地使恶化.
- 识别导致恶化的药物对于有效的患者管理至关重要.
研究的目的:
- 为了确定患者的药理管理.
- 为了确定与病变恶化相关的药物.
- 分析患者可能不合适药物的处方模式.
主要方法:
- 一项横截面研究分析了哥伦比亚卫生系统中850万个人的门诊处方数据.
- 鉴定了处方模式,社会人口统计学变量,以及可能不适合的药物.
- 研究了21,604名患者的数据.
主要成果:
- 系统性抗生素 (79.9%) 和视网类药物 (55.7%) 是常见的治疗方法,多西环素是最常见的抗生素.
- 17.2%的患者接受了可能不合适的处方,主要是具有雄激素特性的孕激素 (8.9%).
- 女性患者和患有全身性红斑狼或类风湿性关节炎的患者更有可能获得不适当的处方.
结论:
- 患者经常使用全身抗生素过度治疗,这与临床指导方针相反.
- 很大一部分患者接受了可能不合适的药物,可能会恶化他们的病情.
- 需要改进处方实践,以避免恶化病变.
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