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吸烟与疾病相关数据库:基于NHANES 2013-2018年的全面分析吸烟与422种疾病之间的相关性
Xi Chen1,2, Tengkun Wang1,3, Yushan Tian4
1NHC Key Laboratory of Medical Immunology (Peking University), Department of Immunology, School of Basic Medical Sciences, Peking University, Beijing, China.
这项研究确定了46种与吸烟相关的疾病,包括29种与吸烟积极相关的疾病和17种与吸烟负面相关的疾病. 创建了一个新的在线数据库 (SDCD),以探索这些吸烟与疾病的相关性.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 医疗信息学 医疗信息学
背景情况:
- 吸烟是许多疾病的重要危险因素,已确定30多种吸烟相关疾病 (SAD).
- 关于多种疾病和吸烟之间复杂的相关性,研究有限.
- 很少有研究调查与吸烟有负相关性的疾病,而吸烟者的患病率较低.
研究的目的:
- 利用国家健康和营养检查调查 (NHANES) 数据调查吸烟与各种疾病之间的相关性.
- 开发一个全面的吸烟与疾病相关数据库 (SDCD),供公众访问.
- 对可能与吸烟相关的疾病进行广泛的查.
主要方法:
- 分析了来自NHANES 2013-2018数据集的39,126名受试者.
- 使用R的统计分析来检查基线信息,血液指标和吸烟者与非吸烟者的疾病相关性.
- 将数据和统计数据汇总成在线SDCD.
主要成果:
- 识别了46种与吸烟相关的疾病 (SAD),包括29种与吸烟积极相关的疾病 (SPAD) 和17种与吸烟负面相关的疾病 (SNAD).
- 建立了包括422种疾病在内的吸烟与疾病相关数据库 (SDCD).
- SDCD可以在线访问以进行进一步的研究和探索.
结论:
- 该研究成功确定了46种SAD,包括与吸烟的积极和消极关联.
- SDCD的开发和可访问性为了解吸烟相关的健康风险提供了宝贵的资源.
- 这些发现有助于全面了解吸烟与广泛疾病之间的复杂关系.
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