通过Mgat5的N-糖化对免疫媒介瘤清除施加了可向的约束

Erin E Hollander1,2, Rosemary E Flock3, Jayne C McDevitt1,2

  • 1Department of Medicine and.

JCI insight
|June 24, 2024
PubMed
概括

N-乙葡萄糖胺基转移酶V (Mgat5) 对胰腺癌的生长和转移至关重要. 失去Mgat5增强了抗瘤免疫力和对T细胞中介死亡的敏感性,改善了免疫治疗的结果.

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