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Updated: Jun 23, 2025

Facile Preparation of 4-Substituted Quinazoline Derivatives
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Published on: February 15, 2016

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通过正式 [2 + 4] 循环添加反应,通过使用α-Diazo Pyrazoleamides作为C2 Synthons进行4-Hydroxy-2-quinolinones的二选择性合成

Pei Li1, Maoqing Shi1, Kaixin Yang1

  • 1State Key Laboratory of Anti-Infective Drug Discovery and Development, Guangdong Provincial Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.

Organic letters
|June 24, 2024
PubMed
概括

一个新的催化反应有效地使用α-diazo pyrazoleamides和2-aminophenyl ketones创建4-hydroxy-2-quinolinones,实现高立体选择性和产量.

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