Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Optimization of restraint system parameters for reclined drivers in frontal collisions based on finite element modeling.

Traffic injury prevention·2026
Same author

Integrative machine learning and network toxicology framework for assessing environmental pollutant TCDD-induced osteoarthritis risk: a computational cheminformatics approach.

Frontiers in pharmacology·2026
Same author

Nanozyme-engineered liners for proactive prevention of wear particle-induced osteolysis.

Nature communications·2026
Same author

Lower expression of BRCA1 in cardiomyoblast alters the expression of apoptotic, inflammatory and metabolic pathway genes, and enhances catecholamine-induced hypertrophic response.

Gene·2026
Same author

Norepinephrine promotes the proliferation, migration, and phenotypic transformation of renal artery vascular smooth muscle cells via ROCK1.

Iranian journal of basic medical sciences·2026
Same author

Engineering peptide-functionalized fermented milk with enhanced DNA-protective, antioxidant and anti-inflammatory properties via ultrasound-assisted enzymolysis.

Food research international (Ottawa, Ont.)·2026

相关实验视频

Updated: Jun 23, 2025

Author Spotlight: Enhanced Urodynamic Method for Precise Urine Measurement in Awake Mice with Neurogenic Bladder
06:46

Author Spotlight: Enhanced Urodynamic Method for Precise Urine Measurement in Awake Mice with Neurogenic Bladder

Published on: June 7, 2024

686

优化鼠标尿动力学技术,以提高精度.

Aytak Khabbaz1, Kristen Lynn Cohen1, Shengqi Zhang2

  • 1Department of Neurological Surgery, Indiana University School of Medicine; Spinal Cord and Brain Injury Research Group, Stark Neurosciences Research Institute, Department of Neurological Surgery, Goodman and Campbell Brain and Spine, Indiana University School of Medicine.

Journal of visualized experiments : JoVE
|June 24, 2024
PubMed
概括
此摘要是机器生成的。

这项研究引入了一种新的方法,使用蓝酸粘合剂来防止醒着小鼠在囊泡计时的尿液吸收. 这种技术提高了空化体积测量的准确性,并稳定了外部尿道关节电肌图信号.

更多相关视频

Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing
05:25

Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing

Published on: August 14, 2019

19.2K
Evaluating the Procedure for Performing Awake Cystometry in a Mouse Model
09:31

Evaluating the Procedure for Performing Awake Cystometry in a Mouse Model

Published on: May 20, 2017

12.7K

相关实验视频

Last Updated: Jun 23, 2025

Author Spotlight: Enhanced Urodynamic Method for Precise Urine Measurement in Awake Mice with Neurogenic Bladder
06:46

Author Spotlight: Enhanced Urodynamic Method for Precise Urine Measurement in Awake Mice with Neurogenic Bladder

Published on: June 7, 2024

686
Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing
05:25

Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing

Published on: August 14, 2019

19.2K
Evaluating the Procedure for Performing Awake Cystometry in a Mouse Model
09:31

Evaluating the Procedure for Performing Awake Cystometry in a Mouse Model

Published on: May 20, 2017

12.7K

科学领域:

  • 泌尿器科 泌尿器科 泌尿器科 泌尿器科
  • 神经科学是一个神经科学.
  • 生物医学工程 生物医学工程

背景情况:

  • 在清醒的小鼠中精确测量下泌尿道 (LUT) 参数对于研究脊髓损伤 (SCI) 后神经性膀等疾病至关重要.
  • 在小鼠中,传统的囊泡测量被尿液吸收到毛皮和皮肤所挑战,导致低估的空化体积 (VV).
  • 外部尿道关节电肌图 (EUS-EMG) 记录也容易受到清醒,移动动物的工件的影响.

研究的目的:

  • 开发一种改进的方法,用于准确的囊泡测量和EUS-EMG记录在清醒的小鼠.
  • 在泌尿动力学研究期间克服尿液吸收和运动器件的挑战.

主要方法:

  • 在尿道介质和腹部周围使用蓝烯酸粘合剂创建了一个防水皮肤屏障.
  • 这种方法旨在防止尿液吸收和稳定EUS电极.
  • 在清醒的小鼠中同时进行囊泡测量和EUS-EMG记录.

主要成果:

  • 烯酸盐屏障成功地阻止了尿液吸收,由一致的空化体积 (VV) 和残留体积 (RV) 测量与注入体积相匹配的测量证实.
  • 实验后没有观察到任何湿度,这表明有效的尿液制.
  • 稳定的EUS-EMG信号是通过最小化鼠标移动和处理的工件来实现的.

结论:

  • 开发的烯酸盐方法显著提高了醒着小鼠尿动力学测量的准确性.
  • 这种技术对于对LUT功能障碍和神经性膀的可靠临床前研究至关重要.
  • 改进的方法对于推动我们对动物模型中的泌尿病状况的理解至关重要.